acerbic, acid, acrid, aggravating, aggravative, annoying, asperous, astringent, biting, bitter, bothering, bothersome, caustic, chafing, contentious, cutting, disturbing, escharotic, exasperating, exasperative, fretting, galling, grating, grinding, harassing, harsh, importunate, importune, irking, irksome, irritant, irritative, keen, mordant, nose-tickling, penetrating, pesky, pestering, pestiferous, pestilent, pestilential, piercing, piquant, plaguesome, plaguey, plaguing, poignant, provocative, provoking, pungent, rasping, rough, scratchy, severe, sharp, sour, stinging, teasing, tiresome, tormenting, trenchant, troublesome, troubling, vexatious, vexing, vitriolic, wearisome, worrisome, worrying