afflict, bugger, castrate, cripple, de-energize, deactivate, debilitate, derange, devitalize, disable, disarm, disenable, disorder, drain, emasculate, enervate, enfeeble, exhaust, hamstring, hobble, hors de combat, hospitalize, immobilize, impair, inactivate, indispose, invalid, kibosh, lame, lay up, maim, prostrate, put, queer, queer the works, reduce, sabotage, sicken, spike, unfit, weaken, wing, wound, wreck